Selfish genetic elements

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The evolutionary consequences of selfish genetic elements

The traditional view of the genome was once that it is broadly cooperative, with all genes working together amicably to improve the success of the individual as a whole. Benefits to the individual, after all, benefit all the component genes, as fair Mendelian inheritance ensures that all the genes and alleles a parent carries are equally likely to be inherited by an offspring. However, more det...

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Genomes are vulnerable to selfish genetic elements (SGEs), which enhance their own transmission relative to the rest of an individual's genome but are neutral or harmful to the individual as a whole. As a result, genetic conflict occurs between SGEs and other genetic elements in the genome. There is growing evidence that SGEs, and the resulting genetic conflict, are an important motor for evolu...

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ژورنال

عنوان ژورنال: PLOS Genetics

سال: 2018

ISSN: 1553-7404

DOI: 10.1371/journal.pgen.1007700